羊毛及动物毛发弯曲形成的生物学机理研究进展

doi:10.11843/j.issn.0366-6964.2014.05.001

Abstract

Abstract:

Crimp is an important characteristic of wool fiber，and significantly affects wool value，processing and final fabric attributes.Wool crimp is associated with the asymmetric cell division in follicles，well-defined bilateral structure of orthocortex and paracortex，differences in the expression of keratins and keratin-associated proteins and keratinization in fiber.Although rare study was reported on the molecular mechanism of wool crimp formation，the studies in mice showed that these signal pathways of IGFBP5/Krox20，Eda/Edar，Wnt，EGFR/TGF-α，Msx2/Foxn1/Ha3 and several keratin genes and transcription factors have significant influence on the formation of zigzag and waved hair.Comparative analyses of gene expression patterns in skin suggest that the molecular regulation of the basic mechanisms of follicle initiation，development and fiber production are similar in most mammals，which offer available information for studying molecular regulation mechanism of wool crimps.The advances on formation mechanism of wool and hair crimps are reviewed in this article in order to further promote the study on the molecular mechanism of wool crimps.

CLC Number:

S826
S813.24

LU Li-li， DI Jiang， WANG Qiong， YU Li-juan， Lazate·AINIWAER. Research Advances on the Biological Formation Mechanism of Wool and Hair Crimps[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2014, 45(5): 679-685.

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Research Advances on the Biological Formation Mechanism of Wool and Hair Crimps

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